2-氨基-7-氧代-4,5,6,7-四氢-1-苯并噻吩-3-羧酸乙酯合成路线 （共 10 条）
反应条件
sodium methylate in methanol
T=20°C; 1 h;
参考文献
Kharizomenova, I. A.; Kapustina, M. V.; Grinev, A. N.; Sheinker, Yu. N.; Alekseeva, L. M.; Kuleshova, E. F.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 12 p. 1339 - 1342
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 12 p. 1626 - 1629
反应条件
sulfur; triethylamine in 1,4-dioxane
3 h; Reflux;
参考文献
Mohareb, Rafat M.; Sherif, Sherif M.; Moustafa, Hosam El-Dean
Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 8 p. 2078 - 2096
反应条件
potassium hydroxide in methanol
T=20°C; 1 h;
参考文献
Kharizomenova, I. A.; Kapustina, M. V.; Grinev, A. N.; Sheinker, Yu. N.; Alekseeva, L. M.; Kuleshova, E. F.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 12 p. 1339 - 1342
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 12 p. 1626 - 1629
反应条件
potassium hydroxide in methanol
T=20°C; 1 h;
参考文献
Kharizomenova, I. A.; Kapustina, M. V.; Grinev, A. N.; Sheinker, Yu. N.; Alekseeva, L. M.; Kuleshova, E. F.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 12 p. 1339 - 1342
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 12 p. 1626 - 1629
反应条件
potassium hydroxide in methanol
T=20°C; 1 h;
参考文献
Kharizomenova, I. A.; Kapustina, M. V.; Grinev, A. N.; Sheinker, Yu. N.; Alekseeva, L. M.; Kuleshova, E. F.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 12 p. 1339 - 1342
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 12 p. 1626 - 1629
反应条件
1: 64.9 percent / K2Cr2O7 / aq. acetic acid / 1. 65-80 deg C; 2. 20 deg C, 2 h
2: 83 percent / sodium methylate / methanol / 1 h / 20 °C
View Scheme
参考文献
Kharizomenova, I. A.; Kapustina, M. V.; Grinev, A. N.; Sheinker, Yu. N.; Alekseeva, L. M.; Kuleshova, E. F.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 12 p. 1339 - 1342
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 12 p. 1626 - 1629
反应条件
1: 52.1 percent / K2Cr2O7 / aq. acetic acid
2: KOH / methanol / 1 h / 20 °C
View Scheme
参考文献
Kharizomenova, I. A.; Kapustina, M. V.; Grinev, A. N.; Sheinker, Yu. N.; Alekseeva, L. M.; Kuleshova, E. F.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 12 p. 1339 - 1342
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 12 p. 1626 - 1629
反应条件
1: 50.9 percent / K2Cr2O7 / aq. acetic acid
2: KOH / methanol / 1 h / 20 °C
View Scheme
参考文献
Kharizomenova, I. A.; Kapustina, M. V.; Grinev, A. N.; Sheinker, Yu. N.; Alekseeva, L. M.; Kuleshova, E. F.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 12 p. 1339 - 1342
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 12 p. 1626 - 1629
反应条件
1: 39.7 percent / K2Cr2O7 / aq. acetic acid
2: KOH / methanol / 1 h / 20 °C
View Scheme
参考文献
Kharizomenova, I. A.; Kapustina, M. V.; Grinev, A. N.; Sheinker, Yu. N.; Alekseeva, L. M.; Kuleshova, E. F.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 12 p. 1339 - 1342
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 12 p. 1626 - 1629
反应条件
1: 1. NaNO2, conc. HCl; 2. copper acetate / 1. dioxane, -7 to -10 deg C, 20 min; 2. dioxane, ethanol, 70 deg C, 30 min
2: 45.9 percent / NaOH; aq. HCl / ethanol / 0.33 h / Heating
View Scheme
参考文献
Kharizomenova, I. A.; Kapustina, M. V.; Grinev, A. N.; Sheinker, Yu. N.; Alekseeva, L. M.; Kuleshova, E. F.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 12 p. 1339 - 1342
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 12 p. 1626 - 1629
