1-氯-5,6,7-三甲基-6H-吡咯并[3,4-d]吡嗪盐酸盐合成路线 （共 3 条）
反应条件
trichlorophosphate
T=85°C; 4 h;
参考文献
Inel, Sermin; Jones, R. Alan; Ogretir, Cemil
Tetrahedron, 1984 , vol. 40, # 20 p. 3979 - 3986
反应条件
1: aq. NaOH, tetrabutylammonium bromide / CH2Cl2 / 3 h / 0 °C
2: 83 percent / hydrazine hydrate / ethanol / Heating
3: 71 percent / POCl3 / 4 h / 85 °C
View Scheme
参考文献
Inel, Sermin; Jones, R. Alan; Ogretir, Cemil
Tetrahedron, 1984 , vol. 40, # 20 p. 3979 - 3986
反应条件
1: 83 percent / hydrazine hydrate / ethanol / Heating
2: 71 percent / POCl3 / 4 h / 85 °C
View Scheme
参考文献
Inel, Sermin; Jones, R. Alan; Ogretir, Cemil
Tetrahedron, 1984 , vol. 40, # 20 p. 3979 - 3986
