N2-[叔丁氧羰基]-N6-(三氟乙酰基)-D-赖氨酸合成路线 （共 4 条）
反应条件
1: With triethylamine in N,N-dimethyl-formamide
T=20°C; 3 h;
2: With hydrogenchloride in water; N,N-dimethyl-formamide
pH=2;
参考文献
Pestov, Nikolay B.; Okkelman, Irina A.; Shmanai, Vadim V.; Hurski, Alaksiej L.; Giaccia, Amato J.; Shchepinov, Mikhail S.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 255 - 258
反应条件
in methanol
T=23°C; Carboxylation; 3 h;
参考文献
Eid, Clark N.; Nesler, Michael J.; Zia-Ebrahimi, Mohammad; Wu, Chuyn-Yeh Ernie; Yao, Raymond; Cox, Karen; Richardson, John
Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 8 p. 705 - 716
反应条件
1: piperidine, DMF / 0.05 h
2: methanol; various solvent(s) / 2 h
View Scheme
参考文献
Rizo, Josep; Albericio, Fernando; Giralt, Ernest; Pedroso, Enrique
Tetrahedron Letters, 1992 , vol. 33, # 3 p. 397 - 400
反应条件
sodium hydroxide; sodium hydrogencarbonate; sodium carbonate
参考文献
Suzuki; Sasaki; Endo
Chemical and pharmaceutical bulletin, 1976 , vol. 24, # 1 p. 1 - 9
