hydrogen bromide T=60 - 65°C; 1 h;

<b>Multi-step reaction with 2 steps<br /> </b>1: 75 percent / Fremy's salt, KH₂PO₄ / methanol / 0.5 h / Ambient temperature<br />2: 1.) Ac₂O, H₂SO₄; 2.) NaOMe / 1.) MeOH, overnight; 2.) MeOH, 30 min<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '2037554', constants.ctx, '0')">sulfuric acid</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3592982', constants.ctx, '0')">sodium methylate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '385737', constants.ctx, '0')">acetic anhydride</a> <br />&nbsp;1.) MeOH, overnight; 2.) MeOH, 30 min;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: Ag₂O<br />2: 95 percent / CF₃COOH<br />3: 88 percent / H₂O₂, Na₂CO₃, CuSO₄ <br /> <br /> &nbsp;