1-溴-4-(正辛氧基)苯合成路线 （共 15 条）
反应条件
n-butyllithium in tetrahydrofuran N2; BuLi dropping into org. compd. soln. at -78°C, mixt. keeping 3 h, B-compd. soln. addn. dropwise at -78°C, mixt. allowing to warm to room temp. overnight , stirring 1 h with 10percent HCl, extn. (Et2O); org. extracts washing (water), drying, solvent vac. removal;
参考文献
Imrie, Christopher; Loubser, Christa; Engelbrecht, Pieter; McCleland, Cedric W.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 17 p. 2513 - 2523
参考文献
Kanto Kagaku Kabushiki Kaisha
Patent: US5382380 A1, 1995 ;
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; water
8 h; Inert atmosphereReflux;
参考文献
FUJI XEROX CO., LTD.
Patent: US2010/197942 A1, 2010 ;
Location in patent: Page/Page column 6 ;
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=90°C; Stille coupling; 24 h;
参考文献
Aldred, Matthew P.; Vlachos, Panos; Contoret, Adam E. A.; Farrar, Simon R.; Chung-Tsoi; Mansoor, Bassam; Woon, Kai L.; Hudson, Robert; Kelly, Stephen M.; O'Neill, Mary
Journal of Materials Chemistry, 2005 , vol. 15, # 31 p. 3208 - 3213
反应条件
1.1: trimethyl borate; n-butyllithium
1.2: 100 percent / aq. HCl
2.1: aq. Na2CO3; Pd(PPh3)4
View Scheme
参考文献
Nassif, Larissa; Jakli, Antal; Seed, Alexander J.
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2001 , vol. 365, p. 171 - 179
