1: acetic acid; Mg / methanol; dimethylformamide / 75 h / 20 °C 2: 87 percent / 1-hydroxybenzotriazole; dicyclohexylcarbodiimide / dimethylformamide / 25 °C 3: 92 percent / lithium hydroxide monohydrate / methanol; H2O / 2 h / 20 °C View Scheme

magnesium; acetic acid in methanol; N,N-dimethyl-formamide T=20°C; 75 h;