1-三苯甲基-4-碘咪唑合成路线 （共 23 条）
反应条件
N,N-dimethyl-formamide in tetrahydrofuran
1.5 h;
参考文献
Schering Corporation
Patent: US2004/122018 A1, 2004 ;
Location in patent: Page 470 ;
反应条件
1: 4-iodo-1-triphenylmethyl-1H-imidazole With iso-propylmagnesium bromide in tetrahydrofuran; dichloromethane
T=10 - 20°C; 1 h;
2: 2,3-dimethylbenzaldehyde in tetrahydrofuran; dichloromethane
T=10 - 25°C; 1 h;
参考文献
"Joint Stock Company Grindeks"
Patent: EP1918282 A1, 2008 ;
Location in patent: Page/Page column 5 ;
反应条件
ethylmagnesium bromide
1) Et2O, CH2Cl2, 30 min, r.t. 2) 16 h; Yield given. Multistep reaction;
参考文献
Turner, Richard M.; Lindell, Stephen D.; Ley, Steven V.
Journal of Organic Chemistry, 1991 , vol. 56, # 20 p. 5739 - 5740
