N-苄基-4-苯氨基哌啶-4-氰基合成路线 (共 22 条)
反应条件
1: H2SO4
2: conc. HCl / Heating
3: 80 percent / toluene / 240 h / Heating
View Scheme
参考文献
Colapret; Diamantidis; Spencer; Spaulding; Rudo
Journal of Medicinal Chemistry, 1989 , vol. 32, # 5 p. 968 - 974
反应条件
sulfuric acid
1.) 70 deg C; 2.) hexamethylphosphoric triamide, 20 deg C, 24 h; Yield given. Multistep reaction;
参考文献
Parys, Marc Van; Vandewalle, Maurits
Bulletin des Societes Chimiques Belges, 1981 , vol. 90, # 7 p. 749 - 756