1-[(2,2-二乙氧基乙基)硫代]-3-甲氧基-苯合成路线 （共 12 条）
反应条件
1.1: boron trifluoride diethyl etherate / dichloromethane / 0.5 h / 20 °C / Inert atmosphere
1.2: 72 h / 20 °C
2.1: AlCl3, aluminium chloride / dichloromethane / 1.25 h / -75 - -40 °C / Inert atmosphere
2.2: 1.5 h / -40 - 0 °C
3.1: potassium hydroxide; water / tetrahydrofuran / 20 °C / Cooling
3.2: pH 3
View Scheme
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2008/157270 A1, 2008 ;
反应条件
boron trifluoride diethyl etherate in dichloromethane
T=20°C; Inert atmosphere;
参考文献
Industry-University Cooperation Foundation Sogang University
Patent: US2010/261727 A1, 2010 ;
Location in patent: Page/Page column 17 ;
