2-氧代-吡咯烷-3-羧酸合成路线 (共 2 条)
反应条件
1: With anhydrous potassium trimethylsilanolate in tetrahydrofuran
T=20°C;
2: With hydrogenchloride in tetrahydrofuran; diethyl ether
0.333333 h;
参考文献
ARRAY BIOPHARMA INC.; GENENTECH, INC.
Patent: WO2007/146824 A2, 2007 ;
Location in patent: Page/Page column 155 ;
WO 2007/146824 A2
参考文献
Basarab, Gregory S.; Jordan, Douglas B.; Gehret, Troy C.; Schwartz, Rand S.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 12 p. 4143 - 4154