1-氯-2,4-二硝基苯合成路线 （共 755 条）
反应条件
sodium hydride in tetrahydrofuran
T=20°C; 24 h;
参考文献
Schumacher, Richard; Danca, Mihaela Diana; Ma, Jianguo; Herbert, Brian; Nguyen, True Minh; Xie, Wenge; Tehim, Ashok
Patent: US2007/78147 A1, 2007 ;
Location in patent: Page/Page column 72 ;
反应条件
copper(l) iodide; sodium hydride
1.) DMF, 2.) 60 deg C, 3 h;; Yield given. Multistep reaction;
参考文献
Thiruvikraman, Singanallore V.; Suzuki, Hitomi
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 5 p. 1597 - 1598
反应条件
ethanol; sodium ethanolate
参考文献
Heckmann
Justus Liebigs Annalen der Chemie, 1883 , vol. 220, p. 134
Full Text Show Details
Reissert; Heller
Chemische Berichte, 1904 , vol. 37, p. 4369
反应条件
tert.-butylhydroperoxide; potassium tert-butylate in ammonia
T=-33°C;
参考文献
Makosza, Mieczyslaw; Sienkiewicz, Krzysztof
Journal of Organic Chemistry, 1998 , vol. 63, # 13 p. 4199 - 4208
反应条件
tert.-butylhydroperoxide; potassium tert-butylate; ammonia in tetrahydrofuran
0.25 h;
参考文献
Makosza, Mieczyslaw; Sienkiewicz, Krzysztof
Journal of Organic Chemistry, 1990 , vol. 55, # 17 p. 4979 - 4981
参考文献
Hantzsch
Chemische Berichte, 1910 , vol. 43, p. 1651
Chemische Berichte, 1911 , vol. 44, p. 2003
反应条件
1: ethanol / 24 h / Inert atmosphere; Reflux
2: (NH4)2S / ethanol; water / 2.5 h / 65 - 70 °C / Inert atmosphere
3: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane / 18 h / 35 °C / Inert atmosphere
View Scheme
参考文献
Renton, Paul; Green, Brenda; Maddaford, Shawn; Rakhit, Suman; Andrews, John S.
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 3 p. 227 - 231
反应条件
1,4-dioxane; calcium carbonate
参考文献
Deletra; Ullmann
Chem. Zentralbl., 1904 , vol. 75, # I p. 1570
反应条件
1: Py
2: Br2
View Scheme
参考文献
Kharasch,N.; Langford,R.B.
Journal of Organic Chemistry, 1963 , vol. 28, p. 1903 - 1905
参考文献
Albro et al.
Journal of Organic Chemistry, 1949 , vol. 14, p. 771,772
