3-硝基-4-氯苯磺酰胺合成路线 （共 21 条）
反应条件
sulfuric acid; potassium carbonate; acetic acid in N-methyl-acetamide; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethanol; water; ethyl acetate
参考文献
Eli Lilly and Company
Patent: US6281240 B1, 2001 ;
反应条件
sodium carbonate T=130°C;
参考文献
Eastman Kodak Co.
Patent: US2422029 , 1943 ;
参考文献
Novo Nordisk A/S
Patent: US5061706 A1, 1991 ;
反应条件
in 3-methyl-1-butanol
参考文献
Plakidin, Val. L.; Vostrova, V. N.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, p. 295 - 303
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 2 p. 342 - 352
反应条件
in 3-methyl-1-butanol Heating; Product distribution;
参考文献
Plakidin, Val. L.; Vostrova, V. N.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, p. 295 - 303
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 2 p. 342 - 352
反应条件
methanol; potassium hydrosulphide
参考文献
Pappalardo
Gazzetta Chimica Italiana, 1957 , vol. 87, p. 1484,1488
反应条件
pyridine; aniline in dichloromethane
参考文献
Bremberg, Ulf; Caldirola, Patrizia; Jensen, Annika J.; Johansson, Gary; Sutin, Lori; Mott, Andrew; Tejbrant, Jan
Patent: US2003/149019 A1, 2003 ;
US 20030149019 A1
反应条件
sodium carbonate T=130°C;
参考文献
Eastman Kodak Co.
Patent: US2422029 , 1943 ;
反应条件
sodium acetate
5 h; Heating;
参考文献
Shepard; Graham; Hudcosky; Michelson; Scholz; Schwam; Smith; Sondey; Strohmaier; Sugrue
Journal of Medicinal Chemistry, 1991 , vol. 34, # 10 p. 3098 - 3105
反应条件
1: NaOAc / 5 h / Heating
2: Oxone / H2O / 18 h
View Scheme
参考文献
Shepard; Graham; Hudcosky; Michelson; Scholz; Schwam; Smith; Sondey; Strohmaier; Sugrue
Journal of Medicinal Chemistry, 1991 , vol. 34, # 10 p. 3098 - 3105
