5-氨基甲基-2-氯吡啶合成路线 （共 16 条）
反应条件
sodium hydroxide; dihydrogen peroxide; trimethylamine in hydrogenchloride; chloroform; water
参考文献
Nippon Soda Co., Ltd.
Patent: US5744608 A1, 1998 ;
反应条件
1: With hydrogenchloride; water in methanol T=75 - 80°C; 6 h; 2: With sodium hydroxide in methanol; chloroform; water
参考文献
Nippon Soda Co., Ltd.
Patent: US2010/121054 A1, 2010 ;
Location in patent: Page/Page column 9 ;
反应条件
potassium borohydride in ethanol T=25 - 40°C; 2.25 h;
参考文献
WO2011/161615 A1, ;
Page/Page column 58 ;
WO 2011/161615 A1
反应条件
ammonia; hydrogen; Sponge Ni in ethanol T=50°C; Reduction; P=760 Torr; 1.5 h;
参考文献
Tetrahedron Letters, , vol. 40, # 32 p. 5885 - 5888
反应条件
ammonia; hydrogen; Sponge Ni in ethanol T=50°C; Reduction; P=760 Torr; 5 h;
参考文献
Tetrahedron Letters, , vol. 40, # 32 p. 5885 - 5888
反应条件
ammonium hydroxide; sodium hydroxide in acetonitrile
反应条件
sodium hydroxide in ethanol; acetonitrile
反应条件
hydrazine hydrate in ethanol 5 h; Reflux;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 56, # 1 p. 204 - 212
反应条件
in methanol T=20°C; 3 h;
参考文献
Bayer CropScience AG
Patent: US2010/48646 A1, 2010 ;
Location in patent: Page/Page column 27 ;
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2008/124757 A1, 2008 ;
Location in patent: Page/Page column 46-47 ;
WO 2008/124757 A1
