3-氯-[1,1-联苯]-2-羧酸合成路线 （共 6 条）
反应条件
potassium carbonate; silver carbonate in N,N-dimethyl acetamide T=140°C; 16 h; Green chemistry; regioselective reaction;
参考文献
ChemCatChem, , vol. 5, # 10 p. 2839 - 2842
反应条件
1,2,2-trichloro-1,1,2-trichloro-ethane; sec.-butyllithium in tetrahydrofuran; cyclohexane
T=-78 - 20°C;
参考文献
Tilly, David; Samanta, Subhendu S.; Castanet, Anne-Sophie; De, Asish; Mortier, Jacques
European Journal of Organic Chemistry, 2006 , # 1 p. 174 - 182
反应条件
palladium diacetate in water
T=100°C; 3 h; Green chemistry; chemoselective reaction;
参考文献
Wu, Zhiqing; Chen, Si; Hu, Chenxu; Li, Zhengkai; Xiang, Haifeng; Zhou, Xiangge
ChemCatChem, 2013 , vol. 5, # 10 p. 2839 - 2842
反应条件
potassium hydroxide in ethanol
参考文献
Hoover,J.R.E. et al.
J. Med. Chem., 1964 , vol. 7, # 3 p. 245 - 251
反应条件
1: (i) NaNO2, aq. HCl, (ii) CuCl
2: aq. KOH / ethanol
View Scheme
参考文献
Hoover,J.R.E. et al.
J. Med. Chem., 1964 , vol. 7, # 3 p. 245 - 251
反应条件
methanesulfonic acid
T=50 - 60°C;
参考文献
Tilly, David; Samanta, Subhendu S.; Castanet, Anne-Sophie; De, Asish; Mortier, Jacques
European Journal of Organic Chemistry, 2006 , # 1 p. 174 - 182
