3-溴-8-氯-1,5-萘啶合成路线 （共 12 条）
反应条件
1: 8.0 g / 2.5 M NaOH / 1 h / Heating
2: 6.0 g / quinoline / 1 h / Heating
3: 6.4 g / phosphoryl chloride / 10 h / Heating
View Scheme
参考文献
Barlin; Tan
Australian Journal of Chemistry, 1985 , vol. 38, # 3 p. 459 - 465
反应条件
1.1: 1.5 h / 90 °C
1.2: 0.67 h / 60 - 70 °C
2.1: Dowtherm™ A / 0.17 h / 235 - 240 °C
3.1: trichlorophosphate / 2 h / |Inert atmosphere; |Reflux
View Scheme
参考文献
Defaux, Julien; Antoine, Maud; Le Borgne, Marc; Schuster, Tilmann; Seipelt, Irene; Aicher, Babette; Teifel, Michael; Guenther, Eckhard; Gerlach, Matthias; Marchand, Pascal
ChemMedChem, 2014 , vol. 9, # 1 p. 217 - 232
