2-溴甲基吡啶-6-甲酸乙酯合成路线 （共 5 条）
反应条件
in tetrahydrofuran T=50°C; 15 h; Inert atmosphereSchlenk technique;
参考文献
Wang, Daoyong; Zavalij, Peter Y.; Vedernikov, Andrei N.
Organometallics, 2013 , vol. 32, # 17 p. 4882 - 4891
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane
T=84°C; Heating / reflux;
参考文献
Gillespie, Paul; Goodnow, Robert Alan; Tilley, Jefferson Wright
Patent: US2006/122256 A1, 2006 ;
Location in patent: Page/Page column 22 ;
US 20060122256 A1
反应条件
1: With phosphorus tribromide in dichloromethane
T=0°C; 2 h;
2: With sodium hydrogencarbonate in dichloromethane
参考文献
Li, James J,; Hamann, Lawrence G.; Ruan, Zheming; Cooper, Christopher B.; Wu, Shung C.; Simpkins, Ligaya M.; Wang, Haixia; Nayeem, Akbar; Krystek, Stanley R.
Patent: US2006/235028 A1, 2006 ;
Location in patent: Page/Page column 29 ;
US 20060235028 A1
反应条件
1: sodium tetrahydroborate
2: tetrabutylammomium bromide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane
View Scheme
参考文献
Labbe, Genevieve; Krismanich, Anthony P.; De Groot, Sarah; Rasmusson, Timothy; Shang, Muhong; Brown, Matthew D.R.; Dmitrienko, Gary I.; Guillemette, J. Guy
Journal of Inorganic Biochemistry, 2012 , vol. 112, p. 49 - 58
反应条件
in neat (no solvent)
48 h; Inert atmosphereSchlenk techniqueReflux;
参考文献
Wang, Daoyong; Zavalij, Peter Y.; Vedernikov, Andrei N.
Organometallics, 2013 , vol. 32, # 17 p. 4882 - 4891
