1: 46 percent / CaCO3 / N,N-dimethyl-acetamide / 45 h / 25 °C
2: 60 percent / aq. NaOH / ethanol / 2 h / Ambient temperature
View Scheme
参考文献
Jones, Terence R.; Calvert, A. Hilary; Jackman, Ann L.; Eakin, M. Allan; Smithers, Michael J.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1468 - 1476
