4,4''-二甲基-1,1':4',1''-三联苯合成路线 （共 42 条）
反应条件
1: 87 percent / pyridine / CHCl3 / 12 h / 20 °C
2: 18.3 percent Chromat. / dppfNiCl2 / tetrahydrofuran / 28 h / Heating
View Scheme
参考文献
Cho, Chul-Hee; Yun, Hee-Sung; Park, Kwangyong
Journal of Organic Chemistry, 2003 , vol. 68, # 8 p. 3017 - 3025
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in benzene
18 h; Heating;
参考文献
Monde, Kenji; Tomita, York; Gilchrist Jr., M. Lane; McDermott, Ann E.; Nakanishi, Koji
Israel Journal of Chemistry, 2000 , vol. 40, # 3-4 p. 301 - 306
反应条件
Ni(PCy3)2Cl2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=90°C; Negishi coupling reaction; 8 h; Inert atmosphere;
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4901 - 4904
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; palladium (II) trifluoroacetate; 18-crown-6 ether; potassium carbonate in supercritical carbon dioxide
T=120°C; Suzuki-Miyaura reaction; P=82508.3 Torr; 18 h;
参考文献
Kuchurov, Ilya V.; Vasil'Ev, Andrei A.; Zlotin, Sergei G.
Mendeleev Communications, 2010 , vol. 20, # 3 p. 140 - 142
反应条件
morpholine; K3PO4*3H2O; NHC-Pd(II)-Im
T=130°C; Suzuki-Miyaura coupling; 24 h; Inert atmosphere;
参考文献
Wang, Zhan-Yong; Chen, Gao-Qi; Shao, Li-Xiong
Journal of Organic Chemistry, 2012 , vol. 77, # 15 p. 6608 - 6614
反应条件
1: 87 percent / 20 percent aq. Na2CO3; Pd(PPh3)4 / 1,2-dimethoxy-ethane / 8 h / Heating
2: 49 percent / 20 percent aq. Na2CO3; Pd(PPh3)4 / benzene / 18 h / Heating
View Scheme
参考文献
Monde, Kenji; Tomita, York; Gilchrist Jr., M. Lane; McDermott, Ann E.; Nakanishi, Koji
Israel Journal of Chemistry, 2000 , vol. 40, # 3-4 p. 301 - 306
反应条件
sodium hydroxide; benzene
参考文献
Gomberg; Pernert
Journal of the American Chemical Society, 1926 , vol. 48, p. 1381
反应条件
lithium aluminium tetrahydride
参考文献
Campbell,T.W.
Journal of the American Chemical Society, 1960 , vol. 82, p. 3126 - 3128
反应条件
1: 87 percent / 20 percent aq. Na2CO3; Pd(PPh3)4 / 1,2-dimethoxy-ethane / 8 h / Heating
2: 49 percent / 20 percent aq. Na2CO3; Pd(PPh3)4 / benzene / 18 h / Heating
View Scheme
参考文献
Monde, Kenji; Tomita, York; Gilchrist Jr., M. Lane; McDermott, Ann E.; Nakanishi, Koji
Israel Journal of Chemistry, 2000 , vol. 40, # 3-4 p. 301 - 306
反应条件
1: (i) AlCl3, CS2, (ii) SOCl2, Py
2: LiAlH4
3: SOCl2, Py
4: LiAlH4
View Scheme
参考文献
Campbell,T.W.
Journal of the American Chemical Society, 1960 , vol. 82, p. 3126 - 3128
