4,4''-二甲基-1,1':4',1''-三联苯合成路线 （共 42 条）
反应条件
1: LiAlH4
2: SOCl2, Py
3: LiAlH4
View Scheme
参考文献
Campbell,T.W.
Journal of the American Chemical Society, 1960 , vol. 82, p. 3126 - 3128
反应条件
1: SOCl2, Py
2: LiAlH4
View Scheme
参考文献
Campbell,T.W.
Journal of the American Chemical Society, 1960 , vol. 82, p. 3126 - 3128
反应条件
2 Pd/C; sodium hydroxide in water
T=100°C; Hiyama Coupling;
参考文献
Mittapelly, Nagaraju; Mukkanti, Khagga; Reguri, Buchi Reddy
Asian Journal of Chemistry, 2014 , vol. 26, # 4 p. 1015 - 1018
反应条件
palladium on activated charcoal; potassium carbonate; triphenylphosphine in water; toluene
T=100°C; Suzuki coupling;
参考文献
Dong, Cheng-Guo; Liu, Tao-Ping; Hu, Qiao-Sheng
Synlett, 2009 , # 7 p. 1081 - 1086
反应条件
in tetrahydrofuran
2.5 h; Ambient temperature; Yield given;
参考文献
Hart, Harold; Harada, Katsumasa; Du, Chi-Jen Frank
Journal of Organic Chemistry, 1985 , vol. 50, # 17 p. 3104 - 3110
反应条件
aluminum oxide; Catalyst M-Chromium oxide; magnesium oxide
T=590 - 600°C;
参考文献
Kotlyarevskii,I.L.; Bardamova,M.I.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, # 11 p. 3640 - 3645,3573 - 3577
反应条件
1: dichloromethane / 4 h / 20 °C / Inert atmosphere
2: Ni(PCy3)2Cl2 / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 8 h / 90 °C / Inert atmosphere
View Scheme
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4901 - 4904
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethanol; water; toluene / 7 h / Inert atmosphere; Reflux
2: bis(acetylacetonate)nickel(II); IPr*HBF4 / tetrahydrofuran; diethyl ether / 1.5 h / 25 °C / Inert atmosphere
View Scheme
参考文献
Jo, Hyunjong; Kim, Chul-Bae; Ryoo, Tae-Yong; Ahn, Bo-Kyoung; Park, Kwangyong
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 12 p. 3749 - 3754
反应条件
1,2-dichloro-benzene; acetylenedicarboxylic acid diethyl ester
Erwaermen mit aethanol. KOH und Behandeln des Reaktionsprodukts mit K3<Fe(CN)6> und Na2CO3 in H2O;
参考文献
McDonald; Campbell
Journal of Organic Chemistry, 1959 , vol. 24, p. 1969,1973
Organic Syntheses, 1973 , vol. Coll. Vol. V, p. 499
反应条件
1: dichloromethane / 4 h / 20 °C / Inert atmosphere
2: Ni(PCy3)2Cl2 / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 8 h / 90 °C / Inert atmosphere
View Scheme
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4901 - 4904
