3,4-二乙基-1H-吡咯-2-羧酸乙酯合成路线 （共 15 条）
反应条件
Yield given. Multistep reaction;
参考文献
Ono, Noboru; Kawamura, Hisayuki; Bougauchi, Masahiro; Maruyama, Kazuhiro
Tetrahedron, 1990 , vol. 46, # 21 p. 7483 - 7496
反应条件
1: 88 percent / NaOH / ethanol; H2O / Heating 2: 71 percent / trifluoroacetic acid / 1 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 45 p. 11030 - 11039
反应条件
1.1: sodium hydroxide / ethylene glycol / 1 h / |Reflux 2.1: trichlorophosphate / 0 °C / |Inert atmosphere 2.2: 10 h / 20 °C / |Inert atmosphere 2.3: 1 h / 20 °C View Scheme
参考文献
Kancharla, Papireddy; Reynolds, Kevin A.
Tetrahedron, 2013 , vol. 69, # 39 p. 8375 - 8385
反应条件
sodium hydroxide in ethanol; water Heating;
参考文献
Roth, Steven D.; Shkindel, Tetyana; Lightner, David A.
Tetrahedron, 2007 , vol. 63, # 45 p. 11030 - 11039
反应条件
sodium hydroxide in ethylene glycol
参考文献
Shevchuk, Sergiy V.; Davis, Julian M.; Sessler, Jonathan L.
Tetrahedron Letters, 2001 , vol. 42, # 13 p. 2447 - 2450
反应条件
potassium hydroxide; sodium hydrogencarbonate in water; ethylene glycol
参考文献
CANON KABUSHIKI KAISHA; EHIME UNIVERSITY
Patent: US2008/171403 A1, 2008 ;
反应条件
P(MeNCH2CH2)3N in tetrahydrofuran; isopropyl alcohol
T=-20 - -15°C; 2 h;
参考文献
Tang; Verkade
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7793 - 7802
反应条件
hydrogenchloride; 1,8-diazabicyclo[5.4.0]undec-7-ene in nitrogen
参考文献
CANON KABUSHIKI KAISHA; EHIME UNIVERSITY
Patent: US2008/171403 A1, 2008 ;
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
10 h; Ambient temperature;
参考文献
Ono, Noboru; Maruyama, Kazuhiro
Chemistry Letters, 1988 , # 9 p. 1511 - 1514
反应条件
in tetrahydrofuran; diethyl ether
参考文献
Iowa State University Research Foundation, Inc.
Patent: US5367084 A1, 1994 ;
