3,4-二乙基-1H-吡咯-2-羧酸乙酯合成路线 （共 15 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in various solvent(s)
T=20°C; Barton-Zard pyrrole synthesis; 2 h;
参考文献
Bhattacharya, Apurba; Cherukuri, Sankara; Plata, Robert Erik; Patel, Nitinchandra; Tamez Jr., Victoriano; Grosso, John A.; Peddicord, Michael; Palaniswamy, Venkatapuram A.
Tetrahedron Letters, 2006 , vol. 47, # 31 p. 5481 - 5484
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran; isopropyl alcohol
15 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Tang; Verkade
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7793 - 7802
反应条件
1: sulfuric acid / chloroform / 10 h / 20 °C
2: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere; Cooling with ice
View Scheme
参考文献
Canon Kabushiki Kaisha; Ehime University
Patent: US7928221 B2, 2011 ;
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane
T=60°C; 3 h; Product distribution; Further Variations:CatalystsReagentsReaction partnerstimes;
参考文献
Setsune, Jun-ichiro; Toda, Masayuki; Watanabe, Keigo; Panda, Pradeepta K.; Yoshida, Takafumi
Tetrahedron Letters, 2006 , vol. 47, # 43 p. 7541 - 7544
反应条件
1: 88 percent / NaOH / ethanol; H2O / Heating
2: 68 percent / H2O / Heating
3: 80 percent / H2O2; pyridine / methanol / Heating
View Scheme
参考文献
Roth, Steven D.; Shkindel, Tetyana; Lightner, David A.
Tetrahedron, 2007 , vol. 63, # 45 p. 11030 - 11039
