(9CI)-1,5,6,7-四氢吡啶并[2,3-d]嘧啶-2-胺合成路线 (共 3 条)
反应条件
ammonia
T=150°C; 7 h;
参考文献
Dozorova, E. N.; Grizik, S. I.; Persianova, I. V.; Syubaev, R. D.; Shvarts, G. Ya.; Granik, V. G.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 2 p. 100 - 104
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 2 p. 154 - 158
反应条件
1: 91 percent / methanol / 2 h / Ambient temperature
2: 81 percent / xylene / 7 h / Heating
3: 71 percent / alcoholic NH3 / 7 h / 150 °C
View Scheme
参考文献
Dozorova, E. N.; Grizik, S. I.; Persianova, I. V.; Syubaev, R. D.; Shvarts, G. Ya.; Granik, V. G.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 2 p. 100 - 104
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 2 p. 154 - 158
反应条件
1: 81 percent / xylene / 7 h / Heating
2: 71 percent / alcoholic NH3 / 7 h / 150 °C
View Scheme
参考文献
Dozorova, E. N.; Grizik, S. I.; Persianova, I. V.; Syubaev, R. D.; Shvarts, G. Ya.; Granik, V. G.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 2 p. 100 - 104
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 2 p. 154 - 158