in 1,4-dioxane 8 h; Heating / reflux;

sodium hydride in N,N-dimethyl-formamide 3 h; Ambient temperature;

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1: 75 percent / lead tetra-acetate / dimethylformamide 2: 79 percent / sodium hydride / dimethylformamide / 3 h / Ambient temperature View Scheme

sodium hydride 1) dimethylacetamide, RT, 1h, 60 deg C, 30 min, 2) RT, 4 h; Yield given. Multistep reaction;

1: diethyl malonate With sodium hydride in isobutyramide T=20°C; 0.5 h; 2: N-benzyl-2H-pyridolt;2,3-dgt;lt;1.3gt;oxazine-2,4 1H-dione in isobutyramide T=110°C; 4 h; 3: With hydrogenchloride in isobutyramide; water T=0°C; pH=3;