2: 83 percent / 2-chloro-1-methylpyridinium methylsulfate, Et3N / CH2Cl2; 1,2-dichloro-ethane / Ambient temperature View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: sodium methylate / 2 h / 15 - 20 &deg;C / |Inert atmosphere<br />2: potassium hydroxide / water / 5 h / 15 - 20 &deg;C<br /> <br /> &nbsp;