4-氯-2-吡啶-2-基-嘧啶合成路线 （共 2 条）
反应条件
trichlorophosphate
3 h; Heating;
参考文献
Medwid, Jeffrey B.; Paul, Rolf; Baker, Jannie S.; Brockman, John A.; Du, Mila T.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1230 - 1241
反应条件
1: 54 percent / NaOEt / ethanol / 18 h / Heating
2: 93 percent / POCl3 / 1,2-dichloro-ethane / Heating
View Scheme
参考文献
Hammerland, Lance G.; Johansson, Martin; Malmstroem, Jonas; Mattsson, Jan P.; Minidis, Alexander B. E.; Nilsson, Karolina; Peterson, Alecia; Wensbo, David; Wallberg, Andreas; Oesterlund, Krister
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 9 p. 2467 - 2469
