3-(2,5-二甲基-1H-吡咯-1-基)苯酚合成路线 （共 2 条）
反应条件
silica gel; toluene-4-sulfonic acid in neat (no solvent)
T=180°C; Paal-Knorr Pyrrole Synthesis; Microwave irradiation;
参考文献
Murugesan, Dinakaran; Mital, Alka; Kaiser, Marcel; Shackleford, David M.; Morizzi, Julia; Katneni, Kasiram; Campbell, Michael; Hudson, Alan; Charman, Susan A.; Yeates, Clive; Gilbert, Ian H.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 7 p. 2975 - 2990
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate
T=20°C; 0.25 h; Inert atmosphere;
2: 3-(2,5-dimethyl-1H-pyrrol-1-yl)phenol T=100°C; Vilsmeier-Haack Formylation; 3 h; Inert atmosphere;
参考文献
Murugesan, Dinakaran; Mital, Alka; Kaiser, Marcel; Shackleford, David M.; Morizzi, Julia; Katneni, Kasiram; Campbell, Michael; Hudson, Alan; Charman, Susan A.; Yeates, Clive; Gilbert, Ian H.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 7 p. 2975 - 2990
