9-(4-乙酰氧基-3-乙酰氧甲基丁基)-2-氨基-6-氯嘌呤合成路线 （共 36 条）
反应条件
1: 78 percent / ammonium formate / 10percent Pd/C / methanol / 0.5 h / Heating 2: 96 percent / ammonia / methanol / 18 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 8 p. 1738 - 1743
反应条件
water; ammonium formate; palladium on charcoal in methanol; i-BuOAc T=50°C; 5 h; Product distribution / selectivity;
参考文献
WO2004/99208 A1, ;
Page 9-10 ;
反应条件
water; ammonium formate; palladium on charcoal in ethyl acetate 2 h; Product distribution / selectivity;
参考文献
WO2004/99208 A1, ;
Page 10 ;
反应条件
water; ammonium formate; palladium on charcoal in ethyl acetate T=50°C; 5 h; Product distribution / selectivity;
参考文献
WO2004/99208 A1, ;
Page 10 ;
反应条件
ammonium formate; palladium on charcoal in methanol; methyl acetate T=40°C; 6.16667 h; Product distribution / selectivity;
参考文献
WO2004/99208 A1, ;
Page 6-7 ;
反应条件
water; potassium carbonate in tetrahydrofuran; methanol T=0°C;
参考文献
Journal of Fluorine Chemistry, , vol. 127, # 7 p. 837 - 841
