2-甲基-2-丙基(2S)-2-[(4-硝基苯基)氨基甲酰]-1-吡咯烷羧酸酯合成路线 (共 3 条)
反应条件
dicyclohexyl-carbodiimide in dichloromethane
T=20°C; 5 h;
参考文献
Zhou, Guo-Chun; Weng, Zhibing; Shao, Xiaoxia; Liu, Fang; Nie, Xin; Liu, Jinsong; Wang, Decai; Wang, Chunguang; Guo, Kai
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 24 p. 6549 - 6554
反应条件
in tetrahydrofuran
T=20°C; 24 h; Inert atmosphere;
参考文献
Pansare, Sunil V.; Kirby, Raie Lene
Tetrahedron, 2009 , vol. 65, # 23 p. 4557 - 4561
反应条件
1: trifluoroacetic acid / dichloromethane / 1 h / 0 °C
2: dicyclohexyl-carbodiimide; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 5 h / 20 °C
3: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
View Scheme
参考文献
Zhou, Guo-Chun; Weng, Zhibing; Shao, Xiaoxia; Liu, Fang; Nie, Xin; Liu, Jinsong; Wang, Decai; Wang, Chunguang; Guo, Kai
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 24 p. 6549 - 6554