7-氯-4-肼基-2-甲基喹啉合成路线 （共 5 条）
反应条件
hydrazine hydrate
T=20 - 150°C; 0.0833333 h; microwave irradiation in sealed tube;
参考文献
Gemma, Sandra; Kukreja, Gagan; Tripaldi, Pierangela; Altarelli, Maria; Bernetti, Matteo; Franceschini, Silvia; Savini, Luisa; Campiani, Giuseppe; Fattorusso, Caterina; Butini, Stefania
Tetrahedron Letters, 2008 , vol. 49, # 13 p. 2074 - 2077
反应条件
1: methanol / 7 h / 40 °C
2: diphenylether / 0.5 h / |Reflux
3: trichlorophosphate / 3 h / |Reflux
4: hydrazine hydrate / |Reflux
View Scheme
参考文献
Luo, Wei; Liu, Yang; Wang, Jian; Guo, Chun; Lu, Wei-Qiang; Cui, Kun-Qiang
Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 3073 - 3079,7
反应条件
1: diphenylether / 0.5 h / |Reflux
2: trichlorophosphate / 3 h / |Reflux
3: hydrazine hydrate / |Reflux
View Scheme
参考文献
Luo, Wei; Liu, Yang; Wang, Jian; Guo, Chun; Lu, Wei-Qiang; Cui, Kun-Qiang
Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 3073 - 3079,7
反应条件
1: trichlorophosphate / 3 h / |Reflux
2: hydrazine hydrate / |Reflux
View Scheme
参考文献
Luo, Wei; Liu, Yang; Wang, Jian; Guo, Chun; Lu, Wei-Qiang; Cui, Kun-Qiang
Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 3073 - 3079,7
反应条件
sodium tetrahydroborate; nickel dichloride in methanol
T=20°C; 0.5 h;
参考文献
Gemma, Sandra; Kukreja, Gagan; Tripaldi, Pierangela; Altarelli, Maria; Bernetti, Matteo; Franceschini, Silvia; Savini, Luisa; Campiani, Giuseppe; Fattorusso, Caterina; Butini, Stefania
Tetrahedron Letters, 2008 , vol. 49, # 13 p. 2074 - 2077
