2-(4-氯苯基)硫代吡啶-3-羰酰氯合成路线 （共 5 条）
反应条件
thionyl chloride
1.5 h; Heating;
参考文献
Monge; Martinez-Merino; Cenarruzabeitia; et al.
European Journal of Medicinal Chemistry, 1985 , vol. 20, # 1 p. 61 - 66
反应条件
1: 60 percent / NaH / various solvent(s) / Heating
2: SOCl2 / dimethylformamide / 1 h / Heating
View Scheme
参考文献
Liegeois; Rogister; Bruhwyler; Damas; Thuy Phuong Nguyen; Inarejos; Chleide; Mercier; Delarge
Journal of Medicinal Chemistry, 1994 , vol. 37, # 4 p. 519 - 525
反应条件
1: 60 percent / NaH / various solvent(s) / Heating
2: SOCl2 / dimethylformamide / 1 h / Heating
View Scheme
参考文献
Liegeois; Rogister; Bruhwyler; Damas; Thuy Phuong Nguyen; Inarejos; Chleide; Mercier; Delarge
Journal of Medicinal Chemistry, 1994 , vol. 37, # 4 p. 519 - 525
反应条件
1: dimethylformamide / 0.5 h / Heating
2: 84 percent / potassium hydroxide / bis-(2-hydroxy-ethyl) ether / 6.5 h / 180 °C
3: thionyl chloride / 1.5 h / Heating
View Scheme
参考文献
Monge; Martinez-Merino; Cenarruzabeitia; et al.
European Journal of Medicinal Chemistry, 1985 , vol. 20, # 1 p. 61 - 66
反应条件
1: 72 percent / pyridine / Ambient temperature
2: 90 percent / dimethylformamide / 0.5 h / Heating
View Scheme
参考文献
Monge; Martinez-Merino; Cenarruzabeitia; et al.
European Journal of Medicinal Chemistry, 1985 , vol. 20, # 1 p. 61 - 66
