sodium hydroxide; sodium hypochlorite in ethyl acetate 0.5 h;

1: NaOMe / 16 h / 40 °C 2: 1.) Ac2O, 2.) 2 N aq. NaOH / 1.) 100 deg C, 3 h, 2.) 80 deg C, 3 h 3: SOCl2 / CH2Cl2 / 2 h / 0 - 5 °C 4: aq. NaOH / ethanol / 4 h / 60 °C 5: 88 percent / 10percent aq. NaOCl, 6 N aq. NaOH / ethyl acetate / 0.5 h View Scheme

1: SOCl2 / CH2Cl2 / 2 h / 0 - 5 °C 2: aq. NaOH / ethanol / 4 h / 60 °C 3: 88 percent / 10percent aq. NaOCl, 6 N aq. NaOH / ethyl acetate / 0.5 h View Scheme

1: 1.) Ac2O, 2.) 2 N aq. NaOH / 1.) 100 deg C, 3 h, 2.) 80 deg C, 3 h 2: SOCl2 / CH2Cl2 / 2 h / 0 - 5 °C 3: aq. NaOH / ethanol / 4 h / 60 °C 4: 88 percent / 10percent aq. NaOCl, 6 N aq. NaOH / ethyl acetate / 0.5 h View Scheme

1: aq. NaOH / ethanol / 4 h / 60 °C 2: 88 percent / 10percent aq. NaOCl, 6 N aq. NaOH / ethyl acetate / 0.5 h View Scheme

1: aq. NaOH / ethanol / 4 h / 60 °C 2: 88 percent / 10percent aq. NaOCl, 6 N aq. NaOH / ethyl acetate / 0.5 h View Scheme