chromium(VI) oxide in sulfuric acid; water; acetone T=-15°C; 0.5 h;

1: 95.8 percent / CrO3 / acetone; H2O; H2SO4 / 0.5 h / -15 °C 2: 73 percent / CF3COOH / 120 h / Ambient temperature 3: 90 percent / LiBEt3H / tetrahydrofuran / -40 - 20 °C 4: 61.7 percent / BuLi / tetrahydrofuran / 1.) 1 h, 0-10 deg C; 2.) -70 deg C 5: 92 percent / CrO3 / acetone; H2O; H2SO4 / 0.5 h / -15 °C View Scheme

1: 95.8 percent / CrO3 / acetone; H2O; H2SO4 / 0.5 h / -15 °C 2: 1.) Al(CH3)3 / 1.) toluene, from RT to Bp, 4 h; 2.) 0 to Rt, 1 h View Scheme

1: 95.8 percent / CrO3 / acetone; H2O; H2SO4 / 0.5 h / -15 °C 2: 73 percent / CF3COOH / 120 h / Ambient temperature 3: 90 percent / LiBEt3H / tetrahydrofuran / -40 - 20 °C View Scheme

bei der langsamen Destillation;