1: With 2-fluoro-pyridine; trifluoromethylsulfonic anhydride in dichloromethane T=-78 - 0°C; Inert atmosphere; 2: With triethylsilane in dichloromethane T=0 - 25°C; Inert atmosphere; 3: With citric acid in tetrahydrofuran; dichloromethane; water T=45°C; 2 h; chemoselective reaction;
参考文献
Pelletier, Guillaume; Bechara, William S.; Charette, Andre B.
Journal of the American Chemical Society, 2010 , vol. 132, # 37 p. 12817 - 12819
1: thiophene With chloromagnesium diisopropylamide in tetrahydrofuran T=20°C; 24 h; 2: 1-piperidinecarboxaldehyde in tetrahydrofuran T=20°C; 27 h; Further stages.;
参考文献
Shilai, Manabu; Kondo, Yoshinori; Sakamoto, Takao
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 4 p. 442 - 444