反应条件
1: palladium diacetate; caesium carbonate; N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine; 3,4,5-trimethoxyphenylboronic acid / dichloromethane; toluene / 80 °C
2: sulfuric acid / toluene / 35 °C
View Scheme
参考文献
Escribano, Ana; Mateo, Ana I.; Martin De La Nava, Eva M.; Mayhugh, Daniel R.; Cockerham, Sandra L.; Beyer, Thomas P.; Schmidt, Robert J.; Cao, Guoqing; Zhang, Youyan; Jones, Timothy M.; Borel, Anthony G.; Sweetana, Stephanie A.; Cannady, Ellen A.; Mantlo, Nathan B.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3671 - 3675