2-(4-甲氧基苯基)环丙烷羧酸乙酯合成路线 （共 14 条）
反应条件
TlPF6; RuCl[(S)-N,N'-(bis(o-(Ph2P)PhCH)-6,6'-diMe-1,1'-biPh2-diNH2] in dichloromethane 14 h; Title compound not separated from byproducts;
参考文献
Helvetica Chimica Acta, , vol. 84, # 10 p. 3063 - 3074
反应条件
1: With water; sodium hydroxide in tetrahydrofuran; ethanol
T=0 - 20°C; 8 h;
2: With hydrogenchloride in water
参考文献
CONNEXIOS LIFE SCIENCES PVT. LTD.; RANGANATH RAO, Jagannath Madanahalli; ARUMUGAM, Nagarajan; ANSARI, Mohd Mudabbir; GUDLA, Chandrasekhar; PACHIYAPPAN, Shanmugam; RAMALINGAM, Manivannan; GEORGE, Jenson; ARUL, George Fernanda; BOMMEGOWDA, Y, Kenchegowda; ANGUPILLAI, Sathesh Kumar; KOTTAMALAI, Ramamoorthy; JIDUGU, Pradeep; RAO, D, Shivanageshwara
Patent: WO2012/11125 A1, 2012 ;
Location in patent: Page/Page column 119-120 ;
WO 2012/011125 A1
反应条件
trifluoroacetic acid; sodium nitrite
T=20°C;
参考文献
Kadzhaeva; Trofimova; Fedotov; Potekhin; Gazzaeva; Mochalov; Zefirov
Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 5 p. 595 - 605
反应条件
trifluoroacetic acid; sodium nitrite
T=20°C; 0.5 h; regioselective reaction;
参考文献
Kadzhaeva; Trofimova; Fedotov; Potekhin; Gazzaeva; Mochalov; Zefirov
Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 5 p. 595 - 605
