反应条件
1: 1.) diisopropylamine, n-butyllithium / 1.) THF, hexane, -60 deg C, 1 h, 2.) THF, from -60 deg C to RT, overnight
2: 76 percent / K2CO3, NaI / acetonitrile / 21 h / Heating
View Scheme
参考文献
Diana; McKinlay; Otto; Akullian; Oglesby
Journal of Medicinal Chemistry, 1985 , vol. 28, # 12 p. 1906 - 1910
