3-碘-2-苯基-色烯-4-酮合成路线 （共 10 条）
反应条件
iodine in dimethyl sulfoxide
T=190°C; 12 h; Reflux;
参考文献
Sagrera, Gabriel; Bertucci, Ana; Vazquez, Alvaro; Seoane, Gustavo
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 10 p. 3060 - 3073
反应条件
iodine cloride; sodium hydrogencarbonate in acetonitrile
T=20°C; 0.0833333 h;
参考文献
Liu, Zhijian; Zhang, Xiaoxia; Larock, Richard C.
Journal of the American Chemical Society, 2005 , vol. 127, # 45 p. 15716 - 15717
反应条件
iodine cloride in dichloromethane
T=-78°C; 2 h;
参考文献
Zhou, Chengxiang; Dubrovsky, Anton V.; Larock, Richard C.
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1626 - 1632
反应条件
1: CuI; Et3N / PdCl2(PPh3)2 / tetrahydrofuran / 16 h / 20 °C
2: I2 / CH2Cl2 / 20 °C
View Scheme
参考文献
Ahmed, Naseem; Dubuc, Celena; Rousseau, Jacques; Benard, Francois; van Lier, Johan E.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 11 p. 3212 - 3216
反应条件
1: CuI; Et3N / PdCl2(PPh3)2 / tetrahydrofuran / 16 h / 20 °C
2: I2 / CH2Cl2 / 20 °C
View Scheme
参考文献
Ahmed, Naseem; Dubuc, Celena; Rousseau, Jacques; Benard, Francois; van Lier, Johan E.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 11 p. 3212 - 3216
反应条件
1: tetrahydrofuran / 0.5 h / -78 °C
2: MnO2 / CHCl3 / 2 h / Heating
3: 99 percent / ICl / CH2Cl2 / 2 h / -78 °C
View Scheme
参考文献
Zhou, Chengxiang; Dubrovsky, Anton V.; Larock, Richard C.
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1626 - 1632
反应条件
1: tetrahydrofuran / 0.5 h / -78 °C
2: MnO2 / CHCl3 / 2 h / Heating
3: 99 percent / ICl / CH2Cl2 / 2 h / -78 °C
View Scheme
参考文献
Zhou, Chengxiang; Dubrovsky, Anton V.; Larock, Richard C.
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1626 - 1632
反应条件
1: MnO2 / CHCl3 / 2 h / Heating
2: 99 percent / ICl / CH2Cl2 / 2 h / -78 °C
View Scheme
参考文献
Zhou, Chengxiang; Dubrovsky, Anton V.; Larock, Richard C.
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1626 - 1632
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / Inert atmosphere
1.2: 16.25 h / 20 °C
2.1: iodine / dimethyl sulfoxide / 12 h / 190 °C / Reflux
View Scheme
参考文献
Sagrera, Gabriel; Bertucci, Ana; Vazquez, Alvaro; Seoane, Gustavo
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 10 p. 3060 - 3073
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / Inert atmosphere
1.2: 16.25 h / 20 °C
2.1: iodine / dimethyl sulfoxide / 12 h / 190 °C / Reflux
View Scheme
参考文献
Sagrera, Gabriel; Bertucci, Ana; Vazquez, Alvaro; Seoane, Gustavo
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 10 p. 3060 - 3073
