1-(2,3-二氢-1,4-苯并二烷-5-基)哌嗪盐酸盐合成路线 （共 4 条）
反应条件
in chlorobenzene Reflux;
参考文献
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL; JIN, Jian; ROTH, Bryan; FRYE, Stephen
Patent: WO2012/3418 A2, 2012 ;
Location in patent: Page/Page column 97 ;
WO 2012/003418 A2
反应条件
1: tri(o-tolyl)phosphine, bis(dibenzylideneacetone)palladium(O), sodium tert-butoxide / toluene / 100 °C 2: trifluoroacetic acid / CH2Cl2 / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 15 p. 2219 - 2222
反应条件
1.1: triethylamine / water; acetone / 0 °C 2.1: sodium azide / water; acetone 2.2: Heating 3.1: hydrogenchloride / water / Reflux 4.1: chlorobenzene / Reflux View Scheme
参考文献
WO2012/3418 A2, ;
WO 2012/003418 A2
反应条件
1: hydrogenchloride / water / Reflux 2: chlorobenzene / Reflux View Scheme
参考文献
WO2012/3418 A2, ;
WO 2012/003418 A2
