反应条件
1: sodium azide / dimethylformamide / 24 h / 50 °C 2: 80 percent / sodium metoxide / methanol / 6 h / Ambient temperature 3: 81 percent / pyridine / 4 h / from 0 deg C to room temp. 4: 94 percent / pyridine / 4 h / Ambient temperature 5: 82 percent / sodium methoxide / dimethylformamide / 0.08 h / 50 °C 6: sodium methoxide / dimethylformamide / 3 h / 50 °C 7: hydrogen / palladium black / ethanol / 1 h 8: aq. sodium bicarbonate / diethyl ether / 2 h / Ambient temperature 9: 1.) 50percent aq. trifluoroacetic acid, 2.) sodium borohydride / 1.) room temp., 15 ethanol, min; 2.) water, room temp., 10 min 10: 70 percent / hydrogen / palladium black / acetic acid / 13 h View Scheme
参考文献
Fleet, George W. J.; Smith, Paul W.
Tetrahedron, 1987 , vol. 43, # 5 p. 971 - 978
