(1-苄基-2-磺酰基-1H-咪唑-5-基)甲醇合成路线 (共 17 条)
反应条件
acetic acid in water; isopropyl alcohol
参考文献
LG Chem Investment Ltd.
Patent: US6630593 B1, 2003 ;
反应条件
1: benzylamine With hydrogenchloride in water; acetonitrile 0.05 h; Cooling with ice; 2: 1.3-dihydroxypropan-2-one; potassium thioacyanate With propionic acid in water; acetonitrile T=70°C; 2 h;
参考文献
Shen, Jianhua; Wang, Yiping; Wang, Kai
Patent: US2014/171431 A1, 2014 ;
Location in patent: Paragraph 0591 ;
反应条件
acetic acid in butan-1-ol 50 h; Ambient temperature;
参考文献
Aulaskari, Paula; Ahlgren, Markku; Rouvinen, Juha; Vainiotalo, Pirjo; Pohjala, Esko; Vepsaelaeinen, Jouko
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 4 p. 1345 - 1354
反应条件
in butan-1-ol T=7°C; 0.5 h; Sonication;
参考文献
Entezari, Mohammad H.; Asghari, Azam
European Journal of Medicinal Chemistry, 2008 , vol. 43, # 12 p. 2835 - 2839
反应条件
acetic acid in water; acetonitrile T=55°C; Marckwald imidazole synthesis; 18 h; Product distribution; Further Variations:Solvents;
参考文献
Journal of Heterocyclic Chemistry, , vol. 40, # 2 p. 229 - 241
参考文献
Pharmacy and Pharmacology Communications, , vol. 4, # 2 p. 99 - 101
反应条件
1: 78 percent / NaOH / methanol; H2O / 20 °C 2: 92.5 percent / MnO2 / CHCl3 / Heating 3: 75 percent / silver nitrate; NaOH / H2O View Scheme
参考文献
Hadizadeh; Tafti
Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 4 p. 841 - 844
反应条件
dihydrogen peroxide; acetic acid in water T=35 - 45°C; caution exothermic; Product distribution; Further Variations:ReagentsTemperatures;
参考文献
Maligres, Peter E.; Waters, Marjorie S.; Weissman, Steven A.; McWilliams, J. Christopher; Lewis, Stephanie; Cowen, Jennifer; Reamer, Robert A.; Volante; Reider, Paul J.; Askin, David
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 2 p. 229 - 241
反应条件
nitric acid in water
参考文献
Farmos Yhtyma-Oy
Patent: US4584383 A1, 1986 ;