反应条件
1: 4-bromo-pyridine With phenyl chloroformate
2: n-propyl Grignard reagent T=-78°C; 0.5 h;
3: With 3,4,5,6-tetrachloro-1,2-benzoquinone; acetic acid in toluene
T=20°C; 16 h;
参考文献
Simeone, Joseph P; Bugianesi, Robert L; Ponpipom, Mitree M; Yang, Yi Tien; Lo, Jane-Ling; Yudkovitz, Joel B; Cui, Jisong; Mount, George R; Ren, Rena Ning; Creighton, Mellissa; Mao, An-Hua; Vincent, Stella H; Cheng, Kang; Goulet, Mark T
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 22 p. 3329 - 3332