反式-4-(苄氧基)环己胺合成路线 (共 4 条)
反应条件
potassium hydroxide in 2-methoxy-ethanol; water
20 h; Heating;
参考文献
Nishi; Tabusa; Tanaka; Shimizu; Nakagawa
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1140 - 1147
反应条件
1: 74 percent / 60percent NaH, DMSO / 1 h / Ambient temperature
2: 83 percent / 85percent KOH / H2O; 2-methoxy-ethanol / 20 h / Heating
View Scheme
参考文献
Nishi; Tabusa; Tanaka; Shimizu; Nakagawa
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1140 - 1147
反应条件
1: 74 percent / 60percent NaH, DMSO / 1 h / Ambient temperature
2: 83 percent / 85percent KOH / H2O; 2-methoxy-ethanol / 20 h / Heating
View Scheme
参考文献
Nishi; Tabusa; Tanaka; Shimizu; Nakagawa
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1140 - 1147
反应条件
potassium carbonate in tetrahydrofuran; water
0.5 h; Ambient temperature;
参考文献
Nishi; Tabusa; Tanaka; Shimizu; Nakagawa
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1140 - 1147