1,1-二溴-2,2-二(氯甲基)环丙烷合成路线 （共 6 条）
反应条件
sodium hydroxide; dibenzo-18-crown-6; 2,3-dimethylbutane-2,3-diol T=40°C; 96 h;
参考文献
Lynch, Kathleen Mondanaro; Dailey, William P.
Journal of Organic Chemistry, 1995 , vol. 60, # 14 p. 4666 - 4668
反应条件
1: methyl lithium LiBr complex / diethyl ether / 4 h / -40 - 0 °C / |Inert atmosphere 2: iodine / diethyl ether / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Goh, Yi Ling; Tam, Eric K.W.; Bernardo, Paul H.; Cheong, Choon Boon; Johannes, Charles W.; William, Anthony D.; Adsool, Vikrant A.
Organic Letters, 2014 , vol. 16, # 7 p. 1884 - 1887
反应条件
sodium; lithium in decane T=73°C; P=14 Torr; 1.5 h; Yield given. Further byproducts given;
参考文献
Belzner, Johannes; Bunz, Uwe; Semmler, Klaus; Szeimies, Guenter; Opitz, Klaus; Schlueter, Arnulf-Dieter
Chemische Berichte, 1989 , vol. 122, p. 397 - 400
反应条件
sodium; lithium in decane T=73°C; P=14 Torr; 1.5 h; Yield given. Further byproducts given;
参考文献
Belzner, Johannes; Bunz, Uwe; Semmler, Klaus; Szeimies, Guenter; Opitz, Klaus; Schlueter, Arnulf-Dieter
Chemische Berichte, 1989 , vol. 122, p. 397 - 400
反应条件
methyllithium in pentane T=-78°C;
参考文献
De Meijere, Armin; Ligang, Zhao; Belov, Vladimir N.; Bossi, Mariano; Noltemeyer, Matthias; Hell, Stefan W.
Chemistry - A European Journal, 2007 , vol. 13, # 9 p. 2503 - 2516
反应条件
sodium; lithium in decane T=73°C; P=14 Torr; 1.5 h; Yield given. Further byproducts given;
参考文献
Belzner, Johannes; Bunz, Uwe; Semmler, Klaus; Szeimies, Guenter; Opitz, Klaus; Schlueter, Arnulf-Dieter
Chemische Berichte, 1989 , vol. 122, p. 397 - 400
