N-甲基-1H-吲哚-5-乙基磺酰胺合成路线 (共 12 条)
反应条件
1: With potassium hydroxide in ethanol Reflux; 2: With water in ethanol T=10 - 20°C; Product distribution / selectivity;
参考文献
USV LIMITED
Patent: WO2009/118753 A2, 2009 ;
Location in patent: Page/Page column 27 ;
反应条件
1.1: trifluoroacetic acid / ethanol / 25 °C / Reflux 1.2: 10 - 15 °C / pH 8 2.1: hydrogen; acetic acid / palladium 10 on activated carbon / 25 °C / 1448.05 - 2172.08 Torr 2.2: 10 °C / pH 7.5 - 8.5 3.1: hydrogenchloride / isopropyl alcohol; acetone / 5 - 10 °C / pH 1 View Scheme
参考文献
CIPLA LIMITED; RAO, Dharmaraj Ramachandra; KANKAN, Rajendra Narayanrao; CHIKHALIKAR, Sandip Vasant; GHAGARE, Maruti; CURTIS, Philip Anthony
Patent: WO2011/21000 A2, 2011 ;