3-氨基-2,3,4,5-四氢-2-氧代-1H-1-苯并氮杂卓-1-乙酸叔丁酯合成路线 （共 9 条）
反应条件
ammonium formate; palladium 10 on activated carbon in methanol
T=40 - 50°C; 16 h;
参考文献
RANBAXY LABORATORIES LIMITED
Patent: WO2005/9972 A2, 2005 ;
Location in patent: Page/Page column 14 ;
反应条件
hydrogen; nickel in methanol
T=50 - 55°C; P=2068.65 - 2585.81 Torr; 16 h;
参考文献
RANBAXY LABORATORIES LIMITED
Patent: WO2005/9972 A2, 2005 ;
Location in patent: Page/Page column 14 ;
反应条件
ammonium formate; palladium 10 on activated carbon in methanol
T=20°C; 12 h;
参考文献
RANBAXY LABORATORIES LIMITED
Patent: WO2005/9972 A2, 2005 ;
Location in patent: Page/Page column 15 ;
反应条件
ethanolamine
T=80°C; 0.0833333 h;
参考文献
Boyer; Pfund r.; Portmann; Sedelmeier; Wetter
Helvetica Chimica Acta, 1988 , vol. 71, # 2 p. 337 - 343
反应条件
palladium in ethanol
参考文献
Merck and Co., Inc.
Patent: US4757068 A1, 1988 ;
US 4757068 A
反应条件
ammonium chloride; zinc in ethanol; water
0.166667 h; Heating;
参考文献
Lin, Wenqing; Zhang, Xiaomei; He, Ze; Jin, Yi; Gong, Liuzhu; Mi, Aiqiao
Synthetic Communications, 2002 , vol. 32, # 21 p. 3279 - 3284
反应条件
1: 93 percent / kalium-(tert-butylat) / dimethylformamide / 1 h / 0 - 5 °C
2: 85 percent / 2-aminoethanol / 0.08 h / 80 °C
View Scheme
参考文献
Boyer; Pfund r.; Portmann; Sedelmeier; Wetter
Helvetica Chimica Acta, 1988 , vol. 71, # 2 p. 337 - 343
反应条件
1: 83 percent / dimethylformamide / 16 h / 60 °C
2: 93 percent / kalium-(tert-butylat) / dimethylformamide / 1 h / 0 - 5 °C
3: 85 percent / 2-aminoethanol / 0.08 h / 80 °C
View Scheme
参考文献
Boyer; Pfund r.; Portmann; Sedelmeier; Wetter
Helvetica Chimica Acta, 1988 , vol. 71, # 2 p. 337 - 343
反应条件
1: 93 percent / kalium-(tert-butylat) / dimethylformamide / 1 h / 0 - 5 °C
2: 85 percent / 2-aminoethanol / 0.08 h / 80 °C
View Scheme
参考文献
Boyer; Pfund r.; Portmann; Sedelmeier; Wetter
Helvetica Chimica Acta, 1988 , vol. 71, # 2 p. 337 - 343
