二甲基2,2-氮丙啶二羧酸酯合成路线 （共 4 条）
反应条件
ammonia in acetonitrile
T=0°C; 24 h;
参考文献
Antolini, L.; Forni, A.; Moretti, I.; Schenetti, L.; Prati, F.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1992 , # 9 p. 1541 - 1544
反应条件
hydrogenchloride in methanol
参考文献
Prosyanik, A. V.; Bondarenko, S. V.; Loban', S. V.; Markov, V. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985 , vol. 21, # 3 p. 285 - 291
Khimiya Geterotsiklicheskikh Soedinenii, 1985 , vol. 21, # 3 p. 346 - 351
反应条件
sodium methylate
1.) methanol, room temp., 5 min; 2.) benzene, methanol, 60 deg C.,10 min;
参考文献
Prosyanik, A. V.; Moskalenko, A. S.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 11 p. 2256 - 2257
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 11 p. 2466 - 2467
反应条件
1: 60 percent / Br2 / CCl4 / 0 - 5 °C
2: 51 percent / NH3 / acetonitrile / 24 h / 0 °C
View Scheme
参考文献
Antolini, L.; Forni, A.; Moretti, I.; Schenetti, L.; Prati, F.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1992 , # 9 p. 1541 - 1544
