T=120°C; P=20 Torr; 0.25 h;

<b>Multi-step reaction with 4 steps<br /> </b>1: 1.) n-butyl-lithium / 1.) hexane, THF, 0 deg C, 15 min 2.) 1 h, hexane, THF<br />2: 1.) n-butyl-lithium, TMEDA 2.) n-butyl-lithium / 1.) hexane, THF, 0 deg C, 15 min 2.) 30 min, hexane, THF<br />3: 49 percent / toluene-p-sulphonic acid / benzene / 0.02 h<br />4: 100 percent / sodium periodate / H₂O; methanol / 18 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 1.) n-butyl-lithium / 1.) hexane, THF, 0 deg C, 15 min 2.) 1 h, hexane, THF<br />2: 1.) n-butyl-lithium, TMEDA 2.) n-butyl-lithium / 1.) hexane, THF, 0 deg C, 15 min 2.) 30 min, hexane, THF<br />3: 49 percent / toluene-p-sulphonic acid / benzene / 0.02 h<br />4: 100 percent / sodium periodate / H₂O; methanol / 18 h / Ambient temperature<br /> <br /> &nbsp;