5’-(4,4’-二甲氧基三苯基)-3’-脱氧胸苷 2’-(2-氰乙基-N,N-二异丙基)亚磷酰胺合成路线 (共 12 条)
反应条件
1: tetrazole / acetonitrile 2: pyridine / 8 h View Scheme
参考文献
Wang, Weimin; Song, Quanlai; Jones, Roger A.
Tetrahedron Letters, 1999 , vol. 40, # 51 p. 8971 - 8974
反应条件
1.1: trichloroacetic acid / dichloromethane / Automated synthesizer; solid phase reaction 1.2: Automated synthesizer; solid phase reaction 2.1: nuclease P1; alkaline phosphatase / Enzymatic reaction View Scheme
参考文献
Sallamand, Corinne; Miscioscia, Audrey; Lartia, Remy; Defrancq, Eric
Organic Letters, 2012 , vol. 14, # 8 p. 2030 - 2033