吗啉-4-基哌嗪-1-基甲酮合成路线 （共 2 条）
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; 2 h;
参考文献
Flanagan, Jack U.; Atwell, Graham J.; Heinrich, Daniel M.; Brooke, Darby G.; Silva, Shevan; Rigoreau, Laurent J.M.; Trivier, Elisabeth; Turnbull, Andrew P.; Raynham, Tony; Jamieson, Stephen M.F.; Denny, William A.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 967 - 977
反应条件
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / 0 - 20 °C
2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
View Scheme
参考文献
Flanagan, Jack U.; Atwell, Graham J.; Heinrich, Daniel M.; Brooke, Darby G.; Silva, Shevan; Rigoreau, Laurent J.M.; Trivier, Elisabeth; Turnbull, Andrew P.; Raynham, Tony; Jamieson, Stephen M.F.; Denny, William A.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 967 - 977
