(1R,2S)-(-)-反-2-苯基-1-环己醇合成路线 (共 53 条)
反应条件
hydrogen; nickel in methanol P=5171.5 Torr; 45 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 62, # 6 p. 1668 - 1674
反应条件
(1S,3R,4S,5R,7R)-N-hydroxy-4-benzyl-1-isopropyl-2-azaadamantane; sodium hydrogencarbonate in dichloromethane T=-40°C; 3 h; Resolution of racemateInert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Organic Letters, , vol. 11, # 8 p. 1828 - 1831
反应条件
acetamide; sodium naphthalenide in tetrahydrofuran T=-78°C; Reduction; 1.5 h;
参考文献
Asensio, Gregorio; Cuenca, Ana; Rodriguez, Nuria; Medio-Simon, Mercedes
Tetrahedron Asymmetry, 2003 , vol. 14, # 24 p. 3851 - 3855
反应条件
hydrogenchloride in tetrahydrofuran T=20°C; Hydrolysis; 0.5 h;
参考文献
Organic Letters, , vol. 2, # 8 p. 1061 - 1063
反应条件
camphor-10-sulfonic acid; water in tetrahydrofuran; acetonitrile T=100°C; 6 h;
参考文献
Selenski, Carolyn; Pettus, Thomas R. R.
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9196 - 9203
反应条件
camphor-10-sulfonic acid; water in tetrahydrofuran; acetonitrile T=100°C; 6 h;
参考文献
Selenski, Carolyn; Pettus, Thomas R. R.
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9196 - 9203
反应条件
diisobutylaluminium hydride in toluene T=-78 - 0°C; Inert atmosphere;
参考文献
Tetrahedron Asymmetry, , vol. 24, # 1 p. 23 - 36
反应条件
(2,6-t-Bu2-4-Me-C6H2O)2AlMe in toluene T=-78 - -15°C;
参考文献
Journal of Organic Chemistry, , vol. 62, # 6 p. 1668 - 1674
反应条件
sulfuric acid in tetrahydrofuran; methanol 1 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 58, # 16 p. 4484 - 4486
反应条件
N-chloro-succinimide; (S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl in tetrahydrofuran T=20°C; 0.166667 h;
参考文献
Sekar; Nishiyama
Journal of the American Chemical Society, 2001 , vol. 123, # 15 p. 3603 - 3604